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March 14, 2006

Roskamp Institute Receives Grant from Veterans Administration for Gulf War Veterans Illness

Sarasota/Bradenton, Florida - The Roskamp Institute is pleased to announce that its research scientists have received a three-year grant from the Veterans Administration to fund research on proteomics analysis of cellular responses to Gulf War agents.

Drs. Michael Mullan and Fiona Crawford were funded on their proposed novel approach for identifying biological pathways implicated in the adverse effects of exposure to Gulf War agents. This proposal will utilize state-of-the-art genomics and proteomics resources housed within the Institute and its affiliated laboratories at the James A. Haley VA Hospital to characterize these cellular responses. This technology will be applied to investigate and characterize the response of various types of human cells to agents such as acetylcholinesterase inhibitors (i.e. pyridostigmine bromide, organophosphate pesticides) and anthrax vaccination. By identifying cellular mechanisms modulated in response to the exposures in these simple cell models the scientists at the Institute will determine initial responses to these agents which subsequently become pathological as the disease progresses. This research will increase our understanding of the underlying mechanism of these illnesses as well as presenting targets for potential therapeutic intervention.

Roskamp Institute is devoted to understanding the causes of and finding novel therapies for neuropsychiatric and neurodegenerative disorders and addictions. The Institute has devised a broad range of scientific approaches to understanding the causes of and potential therapies for these disorders with an emphasis on Alzheimer's disease. The Institute was founded by the philanthropic vision of Robert and Diane Roskamp of Sarasota, FL. The Institute occupies a 42,000 square foot facility in Manatee County.


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